Endocrine Abstracts

Patients with growth hormone deficiency (GHD) have increased risk of bone fractures. Despite a well-known decrease in bone mineral density (BMD) and content (BMC) in these patients, these changes in bone mineralization cannot explain the increase in fracture rate alone. The purpose of this study was to evaluate collagen morphology in cortical bone from GHD rats in order to provide a further explanation for the increased fracture rate seen in GHD patients.<p class="abstext...